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 '''Panacis quinquefolis''' is a herbaceous perennial plant in the ivy family, commonly used as Chinese or Herbal medicine. An extract is sold as Coldcold-fXfx. It is native to eastern North America, though it is also cultivated in places such as China. 

Like Panax ginseng, American ginseng contains dammarane-type ginsenosides, or saponins, as the major biologically active constituents. Dammarane-type ginsenosides include two classifications: 20(S)-protopanaxadiol (PPD) and 20(S)-protopanaxatriol (PPT). American ginseng contains high levels of Rb1, Rd (PPD classification), and Re (PPT classification) ginsenosides—higher than that of P. ginseng in one study.<ref name="chemical composition"/>

{{Leaf|simpleSimple|ovelOvel|}}.

{{Flower|Unisexual|2-4cm long|white–violetWhite–violet|10-18|Flowers are Large, hooded and occur in slender racemes or lax leafy panicles. Corolla is hairy. Carpels are five in number}}

Ginseng has fairly stringent environmental requirements. It requires at least 70 percent shade. The soil must have enough base nutrients (15-20 percent base saturation) to meet its needs, but not so much that the soil pH exceeds 6 (liming is out of the question unless pH is too low). The soil must be moist, but well-drained. To achieve this, the organic matter content has to be pretty high.<ref name="How to plant/cultivate"/>

<ref name="chemical composition">[https://en.wikipedia.org/wiki/American_ginseng "Chemical components"]</ref><ref name="How to plant/cultivate">[https://extension.psu.edu/history-and-cultivation-of-ginseng "Cultivation"]</ref>