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Plithotaxis, from the Greek, πλήΘος, denoting crowd, swarm, or throng. In collective cellular migration, plithotaxis is the tendency for each individual cell within a monolayer to migrate along the local orientation of the maximal principal stress, or equivalently, minimal intercellular shear stress. Plithotaxis requires force transmission across many cell-cell junctions and therefore is an emergent property of the cell group.