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The root bark and heartwood contain xanthones. The xanthones exhibited anti-inflammatory activity in ratsagainst carrageenan-induce oedema; also CNS depressant activity. Jacareubin and 6-deoxy derivatives exhibited antiulcer activity in rats. Calophyllolide, a complex 5-Phcoumarin isolated from nuts, showed antiarrhythmic (as effective as quinidine), bradycardiac coronary dilator, and anticoagulant, also anti-inflammatory and antiarthritic activity. <ref name="Chemical composition"/>

{{Leaf|Simple|Opposite|Leaves broadly elliptic-oblong or obovate, cuneate to rounded at base, slightly recurved and margined, rounded, acute, slightly emarginate, retuse or sub-acute at apex, 6-15 x 3-10.5 cm, coriaceous, glabrous; midnerve channelled above; raised beneath; lateral nerves 4-20 pairs; petioles flat, 1-1.7 cm long, glabrous.}}

{{Flower|Bisexual|axillary racemes|white||Flowers polygamous, 2-2.5 cm across, white, fragrant; bracts ovate, 3-4 mm long, caducous; pedicels 1-3 cm long, glabrous. Sepals 4, reflexed; outer pair ovate to suborbicular, concave, 5.5-6.5 x 4.5-6.5 mm, nerved; the inner subelliptic, 9-15 x 7.5-9.5 mm, petaloid, nerved. Petals usually 4, rarely 3 or 5, obovate to elliptic or oblong, reflexed, 9-12 x 5-9 mm, rarely glabrous, nerved. Stamens (175-) 210-360(-440); filaments 3.5-5.5 mm long, connate for 1.5 mm into 4-6 bundles, cream coloured; anthers rounded or retuse at apex, 0.7-2 mm long. Ovary globose-depressed, 2.5-3 x 2.8-3 mm, stipitate; style 4.5-6.5 mm long; stigmas peltate, 3-5 radiate, 0.7-2 mm across. }}